Chlorine Injury to the Lung
CURRENT CV
 
(The framed picture shown on the upper left corner of the photograph is the original depiction of the pressure-volume diagrams of the lung, chest wall and respiratory system, constructed by Dr. Hermann Rahn at the University of Rochester in 1942)


Home
Up

General Information

Source/Number:                           5U01ES015676 (NIEHS)

Title: Prevention and Treatment of Chlorine Gas Induced
Injury to the Pulmonary System

Funding period:                            09/30/2006 -05/31/2011

This grant is being funded by the Countermeasures Against Chemical Threats Network (CounterACT) (David A. Jett, Ph.D.; Program Director)

View Abstract

Personnel    

                           University of Alabama at Birmingham Investigators

Sadis Matalon, PhD., Principal Investigator
Giuseppe Squadrito, PhD., Co-Investigator
Edward Postlethwait, Ph.D., Co-Investigator
Trenton
R. Schoeb, PhD., Co-Investigator
Rakesh P. Patel, PhD., Co-Investigator
Edward Abraham, M.D., Co-Investigator

Post-Doctoral Fellows   Research Associates
Weifeng Song, MD, PhD   Stephen F Doran, MSc.
 Kokilavani Vedagiri, PhD   Joanna Balaney, BSc.
Shipeng Wei, MD   Kedar Shestra, PhD.
     
Students    Visiting Scholars
 Andreas Bracher   Yongjian Zhou, M.D.
Martin Leustik    
Shawn R. Williams    

Administrative Support
Teri Potter, Assistant to Dr. Matalon
Sandra Roberts, Financial Officer

Southern Research Institute
Larry Bowen, BSc.

Publications

Squadrito, GL, Leustik, M, Doran, S, Bracher, A, Schoeb, TR, Postlethwait, EM, Matalon, S. Mechanisms and modifications of chlorine induced injury to the mammalian lung. FRBM 43:S122, Supplement, 2007.

Squadrito, GL; Williams, SR; Abraham, E; Postlethwait, EM; Matalon, S. Acute chlorine exposure causes severe but short-term hypoxemia and depletion of lung antioxidants. FRBM 41:S96-S96 Suppl.1 2006

Song, W., Lazrak, A. Wei, S. McArdle, P. and Matalon, S. Modulation of lung epithelial sodium  channel function by nitric oxide (2008)  In Free Radical Effects on Membranes, S. Matalon and R.P. Patel, (Eds) Current Topics in Membranes, Vol. 61, in press. San Diego, Elsevier

The Cl2 Exposure Facility